 | ATSF SD45 | Atchison, Topeka and Santa Fe Railway | | | 9 |
 | BN SD45 | Burlington Northern | | | 12 |
 | BPRR SD45M | Buffalo and Pittsburgh Railroad | | | 2 |
 | CNW SD45 | Chicago and North Western Transportation Company | | | 5 |
 | DRGW SD45 | Denver & Rio Grande Western Railroad | | | 2 |
 | EL SD45 | Erie Lackawanna | | | 1 |
 | ICG SD45 | Illinois Central Gulf | | | 1 |
 | NW SD45 | Norfolk and Western Railway | | | 5 |
 | NYSW SD45 | New York, Susquehanna and Western Railway | | | 1 |
 | SBD SD45 | Seaboard System Railroad | | | 1 |
 | SCL SD45 | Seaboard Coast Line Railroad | | | 2 |
 | SLSF SD45 | St. Louis & San Francisco Railway (Frisco) | | | 2 |
 | SOU SD45 | Southern Railway | | | 1 |
 | SP SD45 | Southern Pacific Transportation Company | | | 2 |
 | UP SD45 | Union Pacific Railroad | | | 5 |
 | WC SD45 | Wisconsin Central Ltd. | | | 2 |