In the case of the 57010 the answer would be No, the safety case for DRS requires that if the train is conveying radioactive material then they must have two locos. I think the Ministry of Defense wanted a train to take waste away from Devonport from a decommissioned submarine and then were not ready, so the train returned empty!
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http://charlesgwoodland.smugmug.com/Trains/Recent-Shots-2014/Ju..1&s=A
Shots of the wall reconstruction
http://charlesgwoodland.smugmug.com/Trains/Recent-Shots-2014/Da..W7KmQ
Glad you liked the picture!